Though there is meager study-based information about the nature of emotional disturbances among students in Eastern Ethiopia Universities, the author of this article deems that it could be a common health problem among university students. This very paper aimed at portraying the nature and prevalence of clinical cases seen at the Haramaya University (HU) Counseling and Guidance office, for the past 17 months alone. Mental health services were availed for students of HU, from February 2015 up to June 2016. Overall, two hundred fifty students received the service. Source of bio-data and pattern of distribution of diagnosis was records kept in the office. Fourteen participants, the case of whom culminated in academic withdrawal were excluded. Only 236 participants who received treatment from the office are included. Different types of clinical assessments were used to determine participants’ emotional and psychological distresses. Varying levels of prevalence of psychological problems were found. Most of the students (37.3%) suffered from a clinically significant depression, followed by Anxiety (27%) and Adjustment Disorder (22%). Most of the students (42.8%) were in first year of their education, followed by second year (27.1%) and third year (15.3%). Significant number of these students (37.3%) came from the Institute of Technology (IOT) campus, followed by 18.6% from the College of Business and Economics (FBE), and 12.3% from the College of Humanities and Social Sciences (CHSS). The number of students that sought psychological services, in the past 17 months alone, from the Counseling and Guidance office of HU, depicted the existence of prevailing need. Students’ mental health issue has to get a due attention, as there may be multiple factors that could escalate their predispositions. Keywords: Psychological distress, Intervention-based epidemiological picture.