HIV/AIDS has rapidly established throughout the worlds over the past three decades and has emerged as the important public health problem. Adolescents are at greater risk of acquiring infection because of changing behaviour pattern. More than one third of reported cases of HIV/AIDS in India are among adolescent age. The purpose of the study was to assess the awareness regarding HIV/AIDS of senior secondary school students of tribal and non-tribal area of Himachal Pradesh. In this study 200 student both girls and boys (100 tribal area students and 100 non- tribal area students) from Chamba & Kangra District of Himachal Pradesh selected as sample. The HIV/AIDS awareness tool developed by Kumar (2016) was used to collect the data. The t-test statistical technique was used in this study to analyse the data. The results showed that there is significant difference awareness regarding HIV/AIDS among senior secondary school students of Tribal and Non-Tribal area of Himachal Pradesh. Keywords: Awareness, Secondary school, Tribal and non-tribal area.